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In Nutt published a controversial study on the harms of drug use in The Lancet. Through Drug Science, Nutt has released a number of prominent drug policy reports while launching campaigns in support of evidence-based drug policy. This ranked the harm done to user and society by a range of drugs. Nutt is also campaigning for a change in UK drug laws to allow for more research opportunities. Starting in around , Nutt began talking about bringing to market a compound that could mimic some of the effects of alcohol ethanol - primarily "conviviality" - in humans impacting the GABA receptor  while avoiding the negative health impacts of alcohol; a safer replacement. He calls it "Alcarelle", but does not disclose the exact chemical s.
Early tests used a benzodiazepine derivative, with later adaptations targeting improved efficacy and reduced abuse potential. In Nutt's company GABALabs previously called "Alcarelle" applied for patents for a series of new compounds, branded as Alcarelle,  that more closely mimic the "conviviality" effects of alcohol. The science team at GABA Labs has produced a botanical ingredient which was released to the market in the form of the drink Sentia in January as a "botanical spirit".
In collaboration with Amanda Feilding and the Beckley Foundation , David Nutt is working on the effects of psychedelics on cerebral blood flow. Nutt and his colleagues have already carried out a brain imaging study of people who had taken psilocybin , showing that the chemical played a role in the default mode network , an area of the brain implicated in depression , OCD , and Alzheimer's.
His participation was criticised as, owing to his financial interest in GlaxoSmithKline , he had to withdraw from discussions of the drug paroxetine. As ACMD chairman Nutt repeatedly clashed with government ministers over issues of drug harm and classification. The word equasy derives from equestrianism and other words based on Latin equus , 'horse'. Nutt told The Daily Telegraph that his intention was "to get people to understand that drug harm can be equal to harms in other parts of life". He discovered that riding was "considerably more dangerous than [he] had thought In February he was criticised by Home Secretary Jacqui Smith for stating in the paper that the drug ecstasy was statistically no more dangerous than an addiction to horse-riding. Equasy has been frequently referred to in later discussions of drug harmfulness and drug policies.
The issue of the mismatch between lawmakers' classification of recreational drugs , in particular that of cannabis , and scientific measures of their harmfulness surfaced again in October , after the publication of a pamphlet  containing a lecture Nutt had given to the Centre for Crime and Justice Studies at King's College London in July In this, Nutt repeated his view that illicit drugs should be classified according to the actual evidence of the harm they cause, and presented an analysis in which nine 'parameters of harm' grouped as 'physical harm', 'dependence', and 'social harms' revealed that alcohol or tobacco were more harmful than LSD, ecstasy or cannabis.
In this ranking, alcohol came fifth behind heroin, cocaine, barbiturates and methadone, and tobacco ranked ninth, ahead of cannabis, LSD and ecstasy, he said. In this classification, alcohol and tobacco appeared as Class B drugs, and cannabis was placed at the top of Class C. Nutt also argued that taking cannabis created only a "relatively small risk" of psychotic illness,  and that "the obscenity of hunting down low-level cannabis users to protect them is beyond absurd". Explaining his dismissal of Nutt, Alan Johnson wrote in a letter to The Guardian , that "He was asked to go because he cannot be both a government adviser and a campaigner against government policy.
According to Alan Johnson, the Home Secretary, some contents of this lecture meant I had crossed the line from science to policy and so he sacked me. I do not know which comments were beyond the line or, indeed, where the line was [ This, it was said, would assess whether the body is "discharging the functions" that it was set up to deliver and decide if it still represented value for money for the public. The review was to be conducted by David Omand. When asked if he agreed whether cannabis was less harmful than cigarettes and alcohol, he replied: "I think the scientific evidence is absolutely clear cut.
I would agree with it. On 4 November, the BBC reported that Nutt had financial backing to create a new independent drug research body if the ACMD was disbanded or proved incapable of functioning. In an 11 November editorial in The Lancet , Nutt explicitly attributed his dismissal to a conflict between government and science, and reiterated that "I have repeatedly stated [cannabis] is not safe, but that the idea that you can reduce use through raising the classification in the Misuse of Drugs Act from class C to class B—where it had previously been placed, but thus now increasing the maximum penalty for possession for personal use to 5 years in prison—is implausible.
Nutt reiterated that "The repeated claims by Gordon Brown's government that it had scientific evidence that trumped that of the ACMD and the acknowledgment that it was only interested in scientific evidence that supported its political aims was a cynical misuse of scientific evidence that breached the principles of the Act and was insulting to Council. A subsequent review of policy drafted by Lord Drayson  essentially reaffirmed that the scientific advisers to the government can be dismissed under similar circumstances: "Government and its scientific advisers should not act to undermine mutual trust.
He holds visiting professorships in Australia, New Zealand and the Netherlands. He is a past president of the British Association of Psychopharmacology and of the European College of Neuropsychopharmacology. Nutt is a Patron of My Death My Decision , an organisation which seeks a more compassionate approach to dying in the UK, including the legal right to a medically-assisted death, if that is a person's persistent wish. From Wikipedia, the free encyclopedia. English neuropsychopharmacologist. For other people named David Nutt, see David Nutt. David Nutt's voice.
BBC News. Retrieved 13 January The Guardian. Journal of Psychopharmacology. PMID S2CID The Life Scientific. BBC Radio 4. Retrieved 18 January House of Commons : Ev 1. Retrieved 11 October Retrieved 8 October Insurrection : Attacks on masks in schools aren't just about masks, they're an attempt to destroy public education. Greg Abbott R on Tuesday signed a bill into law that creates strict new voting rules in the state, ending a months-long effort by Democrats to stall the legislation by denying Republicans a quorum in the House.
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